best selling products betulinic acid powder 472-15-1 in bulk

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Model Number:BGH-217
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Product Details

best selling products betulinic acid powder 472-15-1 in bulk
product details

Product name:Betula alba L bark extract

Active ingredient:Betulinic acid

Used Part:bark
Specification: 98%

CAS NO. : 472-15-1

Appearance:White Powder

Flavor: Characteristic taste

Particle Size:80% pass through 80 mesh sieve

Test mothed: HPLC

Molecular formula:C30H48O3

Molecular Weight : 456.71

Extract Solvent: Ethanol & Water

Solubility: Not Soluble in water, lightly soluble in ethanol

Usage: Pharmaceuticals, healthcares,and cosmetics



Product Description
Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase.It is found in the bark of several species of plants, principally the white birch (Betula pubescens) from which it gets its name, but also the ber tree (Ziziphus mauritiana), selfheal (Prunella vulgaris), the tropical carnivorous plants Triphyophyllum peltatum and Ancistrocladus heyneanus, Diospyros leucomelas, a member of the persimmon family, Tetracera boiviniana, the jambul (Syzygium formosanum),flowering quince (Chaenomeles sinensis), rosemary, and Pulsatilla chinensis

Product Analysis


ItemSpecificationResultMethod
BasicProduct Information
Product name472-15-1
Part of the PlantbarkConform/
Country of OriginChinaConform/
Organoleptic Data
AppearanceFine powderConformNLS-QCS-1008
Colorwhite powderConformGB/T 5492-2008
Odor& TasteCharacteristicConformGB/T 5492-2008
Process Data
Solvent(s) UsedWater and ethyl alcoholConform/
Extract ration/Conform
ContentPaeoniflorin≥98%98.18
Drying MethodSpray dryingConform/
ExcipientMaltodextrinConform/
Physical Characteristics
Particle Size (80 mesh)98.0%pass 80meshConformGB/T 5507-2008
Moisture<5.0%2.8%GB/T 14769-1993
Ash Content<4.0%1.4%AOAC 942.05, 18th
Solvent ResidueEur. PharmConformNLS-QCS-1007
Heavy Metals
Total Heavy Metals<10 ppmConformUSP <231>, method II
Arsenic<1.0 ppmConformAOAC 986.15, 18th
Lead<1.0 ppmConformAOAC 986.15, 18th
Mercury<0.5 ppmConformAOAC 971.21, 18th
Pesticide Residue
666<0.2ppmConformGB/T5009.19-1996
DDT<0.2ppmConformGB/T5009.19-1996
Microbiology
Total Plate Count<1,000cfu/g17cfu/gAOAC 990.12, 18th
Total Yeast & Mold<100cfu/g3cfu/gFDA (BAM) Chapter 18, 8th Ed.
E. ColiNegativeNegativeAOAC 997.11, 18th
SalmonellaNegativeNegativeFDA (BAM) Chapter 5, 8th Ed.

Product Function

1.Anti-tumor, anti-HIV agent which induces apoptosis via activation of caspases.

2.The potential of betulinic acid was tested using three human melanoma cell lines, MEL-1, -2, -3, and -4. The growth of all of the cell lines was inhibited significantly by treatment with betulinic acid.

3.Betulinic acid seems to work by inducing (programmed cell death) in cancer cells

4.Betulinic acid has also been found to retard the progression of HIV 1 infection, which eventually leads to , by preventing the formation of syncytia (cellular aggregates).



China best selling products betulinic acid powder 472-15-1 in bulk supplier

best selling products betulinic acid powder 472-15-1 in bulk

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