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Factory Customized Oxidation fermentation stainless steel automatic Bioreactor
Coefficient of charge | 70-75% |
Ventilation ratio | 1-2vvm |
Height-diameter ratio | 2-2.5 |
Tank series | 10L;20L;30L;50L;100L;1-200m3;Customized volume available |
Cultivation medium sterilizing type | Actual sterilization;continuous sterilization;UHT continuous sterilization,etc. |
Culture types | fungus;bacterium,actinomyces |
Culture expanding types | single tank fermentation;multi-stage fermentation;disk-type fermentation |
Heat exchange types | Full jacket;dimple jacket;semicircle-pipe jacket;inner coil,inner turbulation |
Stirring types | turbine stirring,wide blade stirring;paddle stirring;deflector stirring,ect |
Process types
Microbial fermentation,antibiotic fermentation,nucleic acid
fermentation,enzyme fermentation,yeast fermentation,starter
fermentation.
Fermentation types
Oxidation fermentation,facultative fermentation,anaerobic
fermentation.
Material types
Liquid state fermentation,semi-liquid state fermentation,solid
fermentation.
Coefficient of charge
70~75%
Ventilation ratio
1~2vvm
Height-diameter ratio
2~2.5
Culture medium sterilizing type
Actual sterilization,continuous sterilization,UHT continuous
sterilization,etc.
Culture types
fungus,bacterium,actinomyces.
Culture expanding types
Single tank fermentation;multi-stage fermentation,disk-type
fermentation.
Tank series
10L,20L,30L,50L,100L,200L,300L,500L,1m³,2m³,3m³,5m³,10m³,20m³,30m³,50m³,80m³,100m³,customized.
• Fermentation tank structure features:
(1) Design standard:Based on the ASME clean equipment standard to
design and manufacture;complying with the requirements of Pressure
Vessel at the same time;
(2)Inner surface treatment
Mechanical polishing Ra‹0.4μm,and then performing the mirror process;
(3)Outer surface treatment
Mechanical polishing Ra‹0.6μm,and then performing the matting process;
(4)No blind coner treatment
The inner welding line and the inner surface being polished,and
structure components adopting the full length welding,and then
polishing,inner coil pipe using the stress eliminating structure;
(5)Fastener structure
All fasteners using the bolt stud balancing double acorn nuts,PTFE
materia as gasket seal;
(6)Mechanical seal
Using the washable,sterilized collection plate equipped mechanical
seal fixed and moving ring friction sleeve to ensure the friction
debris not falling into the tank;
sealed pattern:dry or wet type,single end face or dual end face;
(7)Heat exchange type
Full Jacket,dimple jacket,semicircle-pipe jacket,inner coil,inner
tubulation;
• Piping system features:
(1) Processing piping
Adopting ASME sanitary grade internal and external polished cleanig
pipe.It is weld automatically with argon gas,inspected by
endoscope.
(2)Valves
The valves connected with tanks all adopting double membrane
combination
diaphragm valve;all steam and compressed air valve are both using
stop valves and sanitary ball valves.
(3)Double membrane diaphragm type tank bottom valve ,sterilizing at
the product outlet before sampling;
(4)Online sterilization
Adopting the clean and saturated steam filtered by 0.5μm titanium rod filter;
(5)Sampling method
Adopting the diaphragm type aseptic sampling valve,doing online
sterilization before sampling and take aseptic sample;
(6)Subcultivation
The pipe can be sterilized during the whole progress,installing the
thermometer to sterilization detection;
(7)Inoculation method
Flame ring type,different pressure type;
(8)Feeding mode
Peristaltic pump,measuring cup,etc.
(9)Multi-stage culture expanding system subcultivation
Subcultivation distributor to do the multitubes distribution
subcultivation valve manifolds subcultivation,etc.