LeaderBio-China Largest Factory Manufacturer Supplier Supply Ethyl Ferulate Inquiry: info@leader-biogroup.com

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LeaderBio-China Largest Factory Manufacturer Supplier Supply Ethyl Ferulate

Inquiry: info@leader-biogroup.com

Hot Line: +86-029-68895030



Product Name: Ethyl Ferulate/ethyl Ferulic acid/Ethyl 4-hydroxy-3-methoxycinnamate
Molecular Formula: C12H14O4
Molecular Weight: 222.24
CAS No.: 4046-02-0
Appearance: White crystalline powder

Ethyl 4-hydroxy-3-methoxycinnamate Chemical Properties
Melting point63-65 °C(lit.)
Boiling point164-166 °C0.5 mm Hg(lit.)
density1.0643 (rough estimate)
refractive index1.4560 (estimate)
storage temp.Sealed in dry,Room Temperature
solubilityChloroform (Slightly), Ethyl Acetate (Slightly)
pka8.88±0.18(Predicted)
formSolid
colorWhite to Off-White
SensitiveLight Sensitive
BRN2696807
Stability:Hygroscopic, Light Sensitive
InChIKeyATJVZXXHKSYELS-FNORWQNLSA-N
LogP1.940 (est)
CAS DataBase Reference4046-02-0(CAS DataBase Reference)
NIST Chemistry Referenceethyl ferulate(4046-02-0)
Safety Information
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-37/39-36
WGK Germany3
Hazard NoteIrritant
HS Code29189900

DescriptionFerulic acid is a hydroxycinnamic acid that is abundant in plants and originally derived from giant fennel (F. communis). This naturally-occurring phenolic has antioxidant activities that provide protection against inflammation and cancer. Ferulic acid ethyl ester is a lipophilic derivative of ferulic acid, demonstrating increased ability to cross cell membranes. Ferulic acid ethyl ester has less antioxidant capacity than ferulic acid in neuronal PC12 cells (IC50 = 66.7 μM for ferulic acid ethyl ester vs. 44.6 μM for ferulic acid, 2,2-diphenyl-1-picrylhydrazyl radical scavenging). However, ferulic acid ethyl ester increases the expression of heme oxygenase-1, Hsp70, and Hsp72, providing neuroprotection against amyloid β-peptide. Moreover, ferulic acid ethyl ester (25 μM) completely prevents cytotoxicity induced by ultraviolet B irradiation of normal human epidermal melanocytes, again associated with an induced expression of heme oxygenase-1 and Hsp70.
Uses

Ferulic acid ethyl ester is an ethyl ester derivative of Ferulic acid (F308900), which is used as an antioxidant and food preservative.


China LeaderBio-China Largest Factory Manufacturer Supplier Supply Ethyl Ferulate Inquiry: info@leader-biogroup.com supplier

LeaderBio-China Largest Factory Manufacturer Supplier Supply Ethyl Ferulate Inquiry: info@leader-biogroup.com

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